CSE 891: Open Problems in Bioinformatics

Instructor: C. Titus Brown, ctb@msu.edu.


CSE 891, section 003; spring 2009, Tu/Th 12:40 PM - 2:00 PM, 1300 Engineering.

One 80 minute lecture, 2 x 40 minute student presentations each week (3 credits).

Prerequisites: graduate standing in the natural sciences and/or engineering, OR permission of instructor.

This course will introduce biologists to computational considerations, and computational scientists to biological considerations, in the context of modern biological "grand challenges". Likely topics include genome-scale annotation, comparative and regulatory genomics, metagenomics, large-scale analysis of experimental data, phylogeny, gene and protein interaction networks, and machine learning techniques. The intention is to cross-fertilize interests and expertise, as well as expose students to considerations in large-scale data analysis and scientific inference.

The course will be graded on reading, attendance, participation, and presentation.

Additional potential topics: genome-scale alignments; RNAi/ncRNA; gene finding; assembly issues; whole-genome phylogenetics; protein structure; databases, data integration, and data warehousing.

Mailing list

To keep up to date with the planned syllabus, lectures, handouts, etc. please join the announcements mailing list.

Lab of Genomics, Evolution and Development / ctb@msu.edu